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Improved focus, memory, and cognitive function
GHK-Cu generally shows better thermal stability in aqueous solutions, while AHK-Cu may require antioxidant systems for long-term formulation stability
A large fraction of the preclinical BPC-157 literature originates from one research group (Sikiric et al., University of Zagreb)
In borderline cases, methylmalonic acid or homocysteine levels may be tested
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However, the largest Phase IIb trial involving 536 subjects failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading Metabolic Pharmaceuticals to terminate development in 2007
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